Medical Science

Started joint research on development of technology for mass production of hydrogen-oxidizing bacteria

Fujifilm and the CO2 Recycling Research Institute have signed a joint research agreement on the development of technology for mass production of hydrogen-oxidizing bacteria. Combining the technologies of both companies, we will establish mass production technology for UCDI hydrogen bacteria that produces alanine, which is used in pharmaceutical ingredients.

On December 23, 2022, Fujifilm signed a joint research agreement with the CO2 Recycling Research Institute (UCDI) on the development of technology for mass production of hydrogen-oxidizing bacteria . UCDI’s original hydrogen-oxidizing bacteria “UCDI Hydrogen Bacteria” will be stably mass-produced, and technology will be developed to efficiently produce alanine, a type of amino acid.

 Fujifilm has applied the production technology it has cultivated for photographic film to improve the production efficiency of biopharmaceutical manufacturing, including the cultivation of microorganisms and cells. We have also developed a next-generation continuous production system for biopharmaceutical active ingredients that integrates biotechnology and production technology, enabling integrated production from cell culture to purification.

 UCDI Hydrogen Bacteria have a high proliferative potential, with 1g of hydrogen-oxidizing bacteria reaching 16 tons after 24 hours, and UCDI’s technology can produce organic substances such as amino acids and alcohols according to the purpose. It is used in a wide range of products, including food, feed, cosmetics, and cell culture media, and demand is expected to grow in the future.

 In the joint research, Fujifilm’s production technology and biotechnology technology will be combined with UCDI’s hydrogen-oxidizing bacteria production technology to quickly establish and socially implement technology to mass-produce alanine by mass-cultivating UCDI hydrogen bacteria. aim. Alanine produced by UCDI hydrogen bacteria is used as an ingredient in pharmaceuticals, and in the field of clinical nutrition, it is also used in oral and enteral nutritional supplements.

 Hydrogen-oxidizing bacteria, which produce organic matter using carbon dioxide as the main raw material, are expected to contribute to a decarbonized society because they can be carbon negative in the process of producing organic matter, in which the amount of carbon dioxide absorbed exceeds the amount emitted. ing.

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